The FRIO Cooling Case will improve the life of anyone dependent on insulin or many other temperature-sensitive medications.The FRIO is a reusable evaporative cooler whose cooling properties do not come from an icepack“ or anything that needs refrigeration. Its cooling properties come from the evaporation of water. When activated, it keeps its temperature under 78F for a minimum of two days, even in temperatures of 100°F. For a FRIO to be activated, simply soak it in water for 5“ 10 minutes. It retains its cooling properties for a minimum of two full days. After that, re-soak it in water and it is good for another two days“ and so on, and so on¦ While a traditional medication cooling case gives you a six to eight hour chain to refrigeration, FRIO cuts that chain. The FRIO offers the security of not being dependent on refrigeration for the life-critical cooling of your insulin. It gives you freedom and flexibility to enjoy life as you choose.